Syringe | Initial nefopam concentration (mg/mL) | Percentage of initial concentration±SD (%) | |||
0 hour | 6 hours | 24 hours | 48 hours | ||
S1 | 2.60 | 100.00±0.26 | 100.28±0.18 | 100.53±0.02 | 100.39±0.02 |
S2 | 2.58 | 100.00±0.22 | 101.14±0.25 | 100.86±0.12 | 101.28±0.12 |
S3 | 2.61 | 100.00±0.15 | 99.78±0.27 | 100.28±0.27 | 99.64±0.20 |
Note: Drug concentrations in samples taken at time zero were designated as 100%. Samples were prepared in triplicate for each syringe.