Evolution of lung function and exercise capacity over follow-up.
| Baseline | 1 year | 2 years | 3 years | ||
| No. patients assessed (%) | 31 (100%) | 20 (65%) | 11 (36%) | 5 (16%) | |
| Mean±SD FVC (% pred) | 61.8±12.1% | 64.7±20.3% | 66.2±14.7% | 71.0±24.7% | |
| DLCO±SD (% pred) | 46.1±19.4% | 50.8±26.8% | 50.0±28.3% | 52.6±26.7% | |
| 6MWT±SD (m) | 334±12 | 341±139 | 265±121 | 286±139 | |
| Change from baseline* | |||||
| FVC±SD (% pred) | — | +2.7±12.1% | +2.2±13.0% | +8.8±18.1% | |
| DLCO±SD (% pred) | — | +3.6±13.4% | +4.2±17.9% | +7.4±21.9% | |
| 6MWT±SD (m) | — | +2±99 | −63±121 | +21±129 | |
| Qualitative evolution (% patients) | |||||
| FVC | Improved | — | 30% | 18% | 40% |
| Stabilised | — | 60% | 82% | 60% | |
| Worsened | — | 10% | 0% | 0% | |
| DLCO | Improved | — | 50% | 18% | 20% |
| Stabilised | — | 45% | 73% | 80% | |
| Worsened | — | 5% | 9% | 0% | |
| 6MWT | Improved | — | 15% | 27% | 60% |
| Stabilised | — | 70% | 18% | 20% | |
| Worsened | — | 15% | 55% | 20% | |
*The change from baseline is referred to the change from the baseline of the patients assessed.
DLCO, carbon monoxide diffusion capacity;FVC, forced vital capacity; 6MWT, 6 min walk test.