Characteristics of patient cohorts exposed to HCQ and REM
| Characteristics | HCQ patients | REM patients | P value |
| n=101 | n=48 | ||
| Age, years | 65.5±15.7 | 62.0±17.0 | 0.147 |
| <40–59 | 35 (34.6) | 16 (33.3) | 0.874 |
| 60–79 | 42 (41.6) | 25 (52.1) | 0.229 |
| ≥80 | 24 (23.8) | 7 (14.6) | 0.197 |
| Gender | |||
| Male | 57 (56.4) | 33 (68.8) | 0.151 |
| Female | 44 (43.6) | 15 (31.2) | |
| Coexisting conditions | |||
| Asthma | 6 (5.9) | 0 | |
| Cancer | 16 (15.8) | 8 (16.7) | 0.898 |
| Chronic kidney disease | 19 (18.8) | 1 (2.1) | 0.005 |
| Diabetes | 32 (31.7) | 13 (27.1) | 0.567 |
| HIV/AIDS | 6 (5.9) | 1 (2.1) | 0.531 |
| Hypertension | 52 (51.5) | 27 (56.3) | 0.586 |
| Medication (at baseline) | |||
| ACE inhibitor or ARB | 31 (30.7) | 23 (47.9) | 0.040 |
| Immunosuppressive drugs | 9 (8.9) | 1 (2.1) | 0.227 |
| Drugs at antiviral prescription | 7.7±3.2 | 6.7±2.7 | 0.723 |
| Drugs during hospital stay | 21.9±13.8 | 23.0±14.1 | 0.602 |
| Body mass index | n=86 | n=48 | |
| Normal/underweight | 36 (41.9) | 28 (58.3) | 0.060 |
| Obese/overweight | 50 (58.1) | 20 (41.7) | |
| Smoking status | n=68 | n=20 | |
| Past smoker | 23 (33.8) | 7 (35.0) | 0.977 |
| Smoker | 6 (8.8) | 2 (10.0) | |
| Never smoked | 39 (57.4) | 11 (55.0) | |
| Hospital stay, days | 22.0±20.9 | 18.0±11.33 | 0.305 |
Data are shown as mean±SD or n (%).
ACE, angiotensin-converting enzyme; ARB, angiotensin-receptor blocker; HCQ, hydroxychloroquine; REM, remdesivir.