Characteristics of clinical cases selected for assessment and its impact based on the CLinical, Economic and Organisational (CLEO) tool
| Characteristics | 30 scenarios for internal reliability | 60 scenarios for external reliability | |||
| N | % | N | % | ||
| Patient age | <18 | 1 | 3.3 | 2 | 3.3 |
| 18–60 | 7 | 23.3 | 8 | 13.3 | |
| ≥60 | 22 | 73.3 | 50 | 83.3 | |
| Patient gender | Women | 22 | 73.3 | 35 | 58.3 |
| Men | 8 | 26.7 | 25 | 41.7 | |
| Clinical specialities | Psychiatry | 3 | 10.0 | 4 | 6.7 |
| Acute care | 8 | 26.7 | 10 | 16.7 | |
| Long-term care | 17 | 56.7 | 43 | 71.7 | |
| Rehabilitation ward | 2 | 6.7 | 3 | 5.0 | |
| Types of drug-related problems | Non-conformity to guidelines/contraindication | 3 | 10.0 | 6 | 10.0 |
| Untreated indication | 2 | 6.7 | 5 | 8.3 | |
| Subtherapeutic dosage | 3 | 10.0 | 6 | 10.0 | |
| Supratherapeutic dosage | 2 | 6.7 | 6 | 10.0 | |
| Drug without indication | 3 | 10.0 | 5 | 8.3 | |
| Drug interaction | 4 | 6.7 | 8 | 13.3 | |
| Adverse drug reaction | 3 | 13.3 | 7 | 11.7 | |
| Improper administration | 4 | 16.7 | 9 | 15.0 | |
| Failure to receive drug | 2 | 6.7 | 3 | 5.0 | |
| Drug monitoring | 4 | 13.3 | 5 | 8.3 | |
| Types of pharmacist interventions | Addition of a new drug | 4 | 13.3 | 6 | 10.0 |
| Drug discontinuation | 4 | 13.3 | 8 | 13.3 | |
| Drug switch | 4 | 13.3 | 10 | 16.7 | |
| Change of administration route | 3 | 10.0 | 6 | 10.0 | |
| Drug monitoring | 5 | 16.7 | 9 | 15.0 | |
| Administration modality optimisation | 5 | 20.0 | 9 | 15.0 | |
| Dose adjustment | 5 | 13.3 | 12 | 20.0 | |
| Clinical impact* | −1: Harmful | 14 | 6.7 | 9 | 1.9 |
| 0: Null | 42 | 20.0 | 50 | 10.4 | |
| 1: Minor | 55 | 26.2 | 121 | 25.2 | |
| 2: Moderate | 43 | 20.5 | 191 | 39.8 | |
| 3: Major | 37 | 17.6 | 100 | 20.8 | |
| 4: Vital | 17 | 8.1 | 9 | 1.9 | |
| Economic impact* | −1: Negative | 34 | 16.2 | 47 | 9.8 |
| 0: Null | 83 | 39.5 | 134 | 27.9 | |
| 1: Positive | 93 | 44.3 | 299 | 62.3 | |
| Organisational impact* | −1: Negative | 12 | 5.7 | 16 | 3.3 |
| 0: Null | 95 | 45.2 | 224 | 46.7 | |
| 1: Positive | 103 | 49.1 | 240 | 50.0 | |
*Percentage was calculated by dividing the number of times each level of each impact was assessed by raters by 210 (7 raters x 30 scenarios) for the internal reliability and by 480 (8 raters x 60 scenarios) for the external reliability.