Characteristics of amikacin samples and patients with amikacin concentration measurements
Characteristics | N (%)* |
Male | 39 (73.6) |
Age, median (range), years | 60 (10–92) |
Prescribed amikacin using course, median (range), days | 13.06 (2–98) |
Patients’ clinical location at the time of sampling | |
Inpatient | 117 (96.7) |
Outpatient | 4 (3.3) |
Indication for sample measurement† | |
Impaired renal function | 23 (43.4) |
Elderly people (>65 years old) | 23 (43.4) |
Combination medication | 46 (86.8) |
Amikacin concentration type | |
Peak concentration | 55 (45.5) |
Trough concentration | 62 (51.2) |
Unknown | 4 (3.3) |
Amikacin prescribing decisions after amikacin concentration | |
Unchanged | 7 (13.2) |
Increased dose rate | 2 (3.8) |
Decreased dose rate | 5 (9.4) |
Multiple dose adjustment | 2 (3.8) |
Change to other antibacterial drugs | 25 (47.2) |
Ceased after the symptoms of infection subsided | 12 (22.6) |
There was a total of 53 patients and 121 amikacin samples.
*Unless otherwise specified.
†Most patients had multiple indications for amikacin sample measurement and we counted the quantity of each type separately.