Parameter		2019 (pre-pandemic period)	2020 (pandemic period)	P value
Total/mean (patient-days)		74.012/10.16	72.742/9.2
Age (years) gender (male%)		8146.5%	7948.5%
Incidence CDI/10 000 patient-days		6.35	2.47	RR= 0.39, p<0.001
Antibiotic consumption DDD/ 100 patient-days
Ceftriaxone	11.68		21.75	p<0.01
Amoxicillin/clavulanic	14.96		10.44	p<0.01
Quinolones	13.67		9.07	p<0.01
Carbapenems	4.39		4.48	p=0.4
Piperacilin/tazobactam	5.13		4.71	p<0.01