Piperacillin/tazobactam content during storage in FOLFusor LV10 (Baxter) elastomeric devices as determined by stability indicating HPLC assay
| Timepoint | 90 mg/mL* | 25 mg/mL† | ||
| PIP+TAZ, % remaining | 95% CI (%) | PIP+TAZ, % remaining | 95% CI (%) | |
| Day 0 | 100.0 (94.1±0.4 mg/mL) | 99.6 to 100.4 | 100 (27.1±0.2 mg/mL) | 99.1 to 100.9 |
| Day 7 | 101.3 | 100.8 to 101.8 | 101.5 | 101.2 to 101.8 |
| Day 10 | 99.7 | 99.5 to 99.9 | 100.3 | 99.9 to 100.7 |
| Day 13 | 98.7 | 98.3 to 99.1 | 99.7 | 99.4 to 100.1 |
| Day 13+1 | 98.0 | 97.8 to 98.2 | 100.9 | 100.3 to 101.5 |
*90 mg/ml total drug concentration: 80 mg piperacillin/10 mg tazobactam.
†25 mg/ml total drug concentration: 22 mg piperacillin/3 mg tazobactam.
PIP, piperacillin; TAZ, tazobactam.