Piperacillin/tazobactam content during storage in Easypump II (B. Braun) elastomeric devices as determined using a stability indicating HPLC assay
| Timepoint | 90 mg/mL* | 25 mg/mL† | ||
| PIP+TAZ, % remaining | 95% CI (%) | PIP+TAZ, % remaining | 95% CI (%) | |
| Day 0 | 100.0 (87.3±0.7 mg/mL) | 99.2 to 100.8 | 100 (24.6±0.5 mg/mL) | 97.9 to 102.1 |
| Day 7 | 101.7 | 101.6 to 101.8 | 100.8 | 100.42 to 101.18 |
| Day 11 | 101.1 | 99.83 to 102.37 | 102.2 | 102.13 to 102.27 |
| Day 13 | 100.7 | 100.6 to 100.8 | 98.9 | 97.35 to 100.45 |
| Day 13+1 | 100.8 | 100.22 to 101.38 | 101.0 | 100.91 to 101.09 |
*90 mg/ml total drug concentration: 80 mg piperacillin/10 mg tazobactam.
†25 mg/ml total drug concentration: 22 mg piperacillin/3 mg tazobactam.
PIP, piperacillin; TAZ, tazobactam.