Table 1

Total amount of cytotoxic agents found on the exterior of the vial from wiping 10 vials

Active drugActive form in vialManufacturer involvedAmount of active ingredient in 10 vials (mg)Amount of active ingredient on surfaces of 10 vials (ng)
Batch 1Batch 2
CyclophosphamidePowder for injectionEndoxan 1 g
(Baxter)
10 00030 ng
>5 and <50
12 ng
>5 and <50
CytarabineLiquidCytarabine 2000 mg/20 mL with plastic overwrap
(Accord Healthecare)
20 000250 ng
>200 and <2000
100 ng
>25 and <250
DoxorubicinLiquidDoxorubicin 50 mg/25 mL with plastic overwrap (Teva Santé)500<10 ng<10 ng
Etoposide phosphatePowder for injectionEtopophos 100 mg
(Bristol-Myers Squibb)
1000<2 ng<2 ng
IfosfamidePowder for injectionHoloxan 2000 mg/50 mL
(Baxter)
20 0005 ng
>0.5 and <10
150 ng
>50 and <200
BusulfanLiquidBusulfan 60 mg/10 mL with plastic overwrap (Fresenius)600<5 ng<5 ng