Table 1

Galenic liquid formulations: composition of the dispersing phases for two crushed tablets; (glycerol) is the glycerol concentration in the final formulation

FormulationLopinavir+ritonavir (mg/mL)Composition(glycerol)
A116.0+4.0Phase 1: ethanol 2 mL, glycerol 1.6 mL; phase 2: water 22 mL6%
A214.9+3.7Phase 1: ethanol 2 mL, glycerol 3 mL; phase 2: water 21.8 mL11%
A314.3+3.6Phase 1: ethanol 2 mL, glycerol 4.2 mL; phase 2: water 21.8 mL15%
A4*14.9+3.7Phase 1: ethanol 2 mL, glycerol 3 mL; phase 2: water 21.8 mL11%
B114.3+3.6Ethanol 2 mL, glycerol 3 mL, water 23 mL11%
B214.3+3.6Water 28 mL
  • *Coating film removed from tablets.