Characteristics of the study sample (n=511)
| Variable | Mean±SD or number | Median, IQR or number (%) |
| Age (years) | 44.63±11.81 | 46.00 (18) |
| Gender (male/female) | 285/226 | 55.8%/44.2% |
| Diagnosis | ||
| Schizophrenia | 257 | 50.3% |
| Bipolar affective disorder | 127 | 24.9% |
| Depression | 127 | 24.9% |
| Length of hospitalisation (days) | 32.26±11.64 | 31.00 (14) |
| Hospitalisation number | ||
| First | 46 | 9% |
| Second | 60 | 11.7% |
| Third | 24 | 4.7% |
| >Third | 381 | 74.6% |
| White blood cell count (х109/L) | 7.02±2.21 | 6.70 (2.7) |
| Red blood cell count (х1012/L) | 4.58±0.51 | 4.57 (0.64) |
| Platelet count (х109/L) | 252.45±69.21 | 248.00 (99) |
| Haemoglobin (g/L) | 139.20±16.45 | 140.00 (18) |
| Erythrocyte sedimentation rate (mm/h) | 15.20±11.88 | 12.00 (13) |
| CRP (mg/L) | 7.13±12.67 | 4.00 (4.2) |
| Glucose (mmol/L) | 5.05±1.07 | 4.90 (0.9) |
| Urea (mmol/L) | 4.39±3.24 | 4.10 (2) |
| Serum creatinine (μmol/L) | 85.11±16.33 | 85.00 (99) |
| Uric acid (μmol/L) | 288.61±127.55 | 278.00 (118) |
| Total proteins (g/L) | 70.11±6.30 | 70.00 (7) |
| Total bilirubin (μmol/L) | 8.63±5.68 | 7.30 (5) |
| Total cholesterol (mmol/L) | 5.15±1.27 | 5.00 (7.1) |
| Тriglycerides (mmol/L) | 1.74±1.04 | 1.48 (1.26) |
| AST (IU/L) | 21.26±13.35 | 18.00 (11) |
| ALT (IU/L) | 24.85±16.75 | 20.00 (14) |
| ALP (IU/L) | 73.63±24.18 | 69.00 (29) |
| GGT (IU/L) | 29.99±22.08 | 23.00 (19) |
| CK (IU/L) | 211.08±314.10 | 102.00 (131) |
| Potassium (mmol/L) | 4.38±0.42 | 4.37 (0.47) |
| Sodium (mmol/L) | 140.61±5.60 | 141.30 (4) |
| Iron (μmol/L) | 15.15±6.59 | 14.30 (8.2) |
| Number of diagnoses | 2.52±1.32 | 2.00 (2) |
| Number of associated comorbidities | 0.59±0.77 | 0.00 (1) |
| Charlson Comorbidity Index (CCI) | 1.08±1.31 | 1.00 (2) |
| Systolic blood pressure (mmHg) | 128.70±19.66 | 130.00 (25) |
| Diastolic blood pressure (mmHg) | 81.40±11.71 | 82.00 (15) |
| Heart rate (beats/min) | 77.85±11.60 | 77.00 (18) |
| Anaemia (yes/no) | 49/462 | 9.6%/90.4% |
| Leucopenia (yes/no) | 12/499 | 2.3%/97.7% |
| Dyslipidaemia (yes/no) | 76/435 | 14.9%/85.1% |
| Hypothyroidism (yes/no) | 26/485 | 5.1%/94.9% |
| Urinary tract infection (yes/no) | 65/446 | 12.7%/87.3% |
| Hypertension (yes/no) | 125/386 | 24.5%/72.8% |
| Constipation (yes/no) | 50/461 | 9.8%/90.2% |
| Respiratory infection (yes/no) | 109/401 | 21.3%/78.5% |
| Heart attack (yes/no) | 17/490 | 3.3%/95.9% |
| Congestive heart failure (yes/no) | 42/469 | 8.2%/91.8% |
| Cerebrovascular accident (yes/no) | 16/495 | 3.1%/96.9% |
| Dementia 0(yes/no) | 17/494 | 3.3%/96.7% |
| COPD (yes/no) | 26/485 | 5.1%/94.9% |
| Rheumatic diseases (yes/no) | 20/491 | 3.9%/96.1% |
| Peptic ulcer disease (yes/no) | 25/486 | 4.9%/95.1% |
| Liver disease (yes/no) | 20/491 | 3.9%/96.1% |
| Diabetes mellitus (yes/no) | 49/462 | 9.6%/90.4% |
| Renal failure (yes/no) | 23/488 | 4.5%/95.5% |
| Tumour (yes/no) | 16/495 | 3.1%/96.9% |
| Smoker (yes/no) | 338/173 | 66.1%/33.9% |
| Alcoholic (yes/no) | 90/421 | 17.6%/82.4% |
| Psychoactive substances (yes/no) | 54/456 | 10.6%/89.2% |
| Allergy (yes/no) | 54/456 | 10.6%/89.2% |
| Number of prescribed drugs | 6.71±2.68 | 6.00,(3) |
| Number of different therapeutic subgroups prescribed (second level of ATC classification) | 4.93±2.17 | 5.00,(3) |
| Analgesics (yes/no) | 24/487 | 4.7%/95.3% |
| Antacids (yes/no) | 69/442 | 13.5%/86.5% |
| Antiarrhythmic drugs (yes/no) | 53/458 | 10.4%/89.6% |
| Antibiotics (yes/no) | 170/341 | 33.3%/66.7% |
| Antiepileptics (yes/no) | 426/85 | 83.4%/16.6% |
| Anticholinergics (yes/no) | 91/420 | 17.8%/82.2% |
| Anticoagulants (yes/no) | 41/470 | 8%/92% |
| Antidepressants (yes/no) | 230/281 | 45%/55% |
| Antidiabetics (yes/no) | 48/463 | 9.4%/90.6% |
| Antihypertensives (yes/no) | 122/389 | 23.9%/76.1% |
| Antihistamines (yes/no) | 29/482 | 5.7%/94.3% |
| Antipsychotics (yes/no) | 499/12 | 97.7%/2.3% |
| Anxiolytics (yes/no) | 469/42 | 91.8%/8.2% |
| Bronchodilators (yes/no) | 38/473 | 7.4%/92.6% |
| Corticosteroids (yes/no) | 44/467 | 8.6%/91.4% |
| Dementia drugs (yes/no) | 17/494 | 3.3%/96.7% |
| Diuretics (yes/no) | 99/412 | 19.4%/80.6% |
| Dopaminergic drugs (yes/no) | 11/500 | 2.2%/97.8% |
| Hypnotics and sedatives (yes/no) | 201/309 | 39.3%/60.5% |
| Laxatives (yes/no) | 50/461 | 9.8%/90.2% |
| Nonsteroidal anti-inflammatory drugs (yes/no) | 97/414 | 19%/81% |
| Statins (yes/no) | 63/448 | 12.3%/87.7% |
| Tetanus vaccine (yes/no) | 23/488 | 4.9%/95.1% |
| Thyroid disease therapy (yes/no) | 25/486 | 23.%/76.3% |
| Vitamins (yes/no) | 121/390 | 4.5%/95.5% |
ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ATC ATC classification, Anatomical Therapeutic Chemical Classification; CK, creatine kinase; COPD, chronic obstructive pulmonary disease; CRP, C-reactive protein; GGT, gamma-g transferase.