Clinical–alimentary tractLow Colectomy Rates in Ulcerative Colitis in an Unselected European Cohort Followed for 10 Years
Section snippets
Colectomy
Status of surgery, including complications, was assessed at the 10-year follow-up visit to the local hospital by interviewing the patients and reviewing hospital records. Colectomy was classified as total abdominal colectomy (TAC) with ileostomy, total proctocolectomy (TPC) with ileostomy, proctocolectomy with ileal pouch anal anastomosis (IPAA), and other operations. Early surgery was defined as colectomy performed within the first 2 years of disease. Acute surgery was defined as colectomy
Follow-up
Nine of the 13 centers complied with the threshold limit of >60% patient identification and response, and a total of 781 patients from these centers were eligible for inclusion in the study. Of these, 690 patients (88%) were followed up for 10 years after diagnosis or until death, whichever came first. The median follow-up time was 123 months (range, 107–144). Ninety-one patients were lost to follow-up, 81 of whom were followed for varying time intervals with a median follow-up time of 46
Discussion
The overall colectomy rate in this European population-based multicenter cohort was 8.7% at 10 years. Disease extent and residence in northern Europe were identified as independent risk factors.
The strengths of the study design are the short inclusion period of only 2 years; the well-defined geographic areas, across Europe and including Israel; the uniform diagnostic criteria; and the inclusion of patients at inception on a population basis. All the patients were followed up during the same
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Supported by the European Commission (QLG4-CT-2000-01414).