Treatment with a proton pump inhibitor improves glycaemic control in type 2 diabetic patients - a retrospective analysis

Diabetes Res Clin Pract. 2010 Dec;90(3):e72-4. doi: 10.1016/j.diabres.2010.09.007.

Abstract

We retrospectively studied whether treatment with esomeprazole improved HbA₁(c) levels in type 2 diabetic patients. We selected 21 patients who had been treated with esomeprazole for 11 ± 3 months and 21 controls. HbA₁(c) levels decreased in the esomeprazole-treated group. Our data indicate that proton pump inhibitors may improve glycaemic control in type 2 diabetic patients.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Blood Glucose
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Esomeprazole / therapeutic use*
  • Female
  • Glycated Hemoglobin / metabolism
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Male
  • Middle Aged
  • Proton Pump Inhibitors / therapeutic use*
  • Retrospective Studies

Substances

  • Blood Glucose
  • Glycated Hemoglobin A
  • Hypoglycemic Agents
  • Proton Pump Inhibitors
  • Esomeprazole