Abstract
Genome-wide screening is anticipated to accelerate the development of personalized medicine by identifying and exploiting new associations between genomic variants and drug responses. However, this goal could be undermined if care is not taken to minimize the impact of pharmacogenomic associations that turn out to have narrower implications than suggested by initial studies.
MeSH terms
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Drug-Related Side Effects and Adverse Reactions
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Genetic Predisposition to Disease / genetics
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Humans
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Incidental Findings*
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Pharmaceutical Preparations / administration & dosage
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Pharmaceutical Preparations / metabolism
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Pharmacogenetics*
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Polymorphism, Genetic / genetics
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Precision Medicine / adverse effects
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Precision Medicine / methods
Substances
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Pharmaceutical Preparations