Background Large F8 deletions represent 3–5% of the variations found in severe
hemophilia A patients, but only a few deletion breakpoints have been characterized …

Introduction With current molecular diagnosis, about 1 to 5% of haemophilia A (HA) patients
remain genetically unresolved. In these cases, deep intronic variation or structural variation …

Background The disease-causative variant remains unidentified in approximately 0.5% to
2% of hemophilia B patients using conventional genetic investigations, and F9 deep intronic …

Introduction Conventional genetic investigation fails to identify the F8 causal variant in 2.5%‐
10% of haemophilia A (HA) patients with non‐severe phenotypes. In these cases, F8 deep …

Le laboratoire d'hémostase des Hospices Civils de Lyon est passé de l'approche
conventionnelle dite fréquentiste à l'approche bayésienne au long cours de gestion des …

Background Prescription computerization is an undeniable step forward in terms of safety. It
can significantly reduce the errors associated with handwritten prescriptions. However these …

Le laboratoire d'hémostase des Hospices Civils de Lyon est passé de l'approche
conventionnelle dite fréquentiste à l'approche bayésienne au long cours de gestion des …

En France, plus de 80% des diagnostics s' appuient sur les examens de biologie médicale,
dont la dépense totale représente 2% des remboursements de la Sécurité Sociale. Dans le …