[HTML][HTML] Drug delivery to the posterior segment of the eye: biopharmaceutic and pharmacokinetic considerations

R Varela-Fernández, V Díaz-Tomé… - Pharmaceutics, 2020 - mdpi.com
The treatment of the posterior-segment ocular diseases, such as age-related eye diseases
(AMD) or diabetic retinopathy (DR), present a challenge for ophthalmologists due to the …

[HTML][HTML] Pharmacokinetics of intravitreal anti-VEGF drugs in age-related macular degeneration

L García-Quintanilla, A Luaces-Rodríguez… - Pharmaceutics, 2019 - mdpi.com
Intravitreal administration of anti-vascular endothelial growth factor (VEGF) antibodies has
become the standard treatment for Age-Related Macular Degeneration; however, the …

[HTML][HTML] A review of population pharmacokinetic analyses of linezolid

E Bandín-Vilar, L García-Quintanilla… - Clinical …, 2022 - Springer
In recent years, many studies on population pharmacokinetics of linezolid have been
conducted. This comprehensive review aimed to summarize population pharmacokinetic …

PET/CT imaging of 3D printed devices in the gastrointestinal tract of rodents

A Goyanes, A Fernández-Ferreiro, A Majeed… - International journal of …, 2018 - Elsevier
Fused deposition modelling (FDM) 3D printing (3DP) is a revolutionary technology with the
potential to transform drug product design in both the pre-clinical and clinical arena. The …

In vitro and in vivo ocular safety and eye surface permanence determination by direct and Magnetic Resonance Imaging of ion-sensitive hydrogels based on gellan …

A Fernández-Ferreiro, MG Barcia… - European Journal of …, 2015 - Elsevier
Gellan gum, kappa-carrageenan and alginates are natural polysaccharides able to interact
with different cations that can be used to elaborate ion-activated in situ gelling systems for …

[HTML][HTML] Cyclodextrin–polysaccharide-based, in situ-gelled system for ocular antifungal delivery

A Fernández-Ferreiro, NF Bargiela… - Beilstein Journal of …, 2014 - beilstein-journals.org
Fluconazole was studied with two different hydrophilic cyclodextrins (hydroxypropyl-β-
cyclodextrin (HPBCD) and sulfobutyl ether-β-cyclodextrin (SBECD)) for the formation of …

[HTML][HTML] 3D printed tacrolimus rectal formulations ameliorate colitis in an experimental animal model of inflammatory bowel disease

I Seoane-Viaño, N Gómez-Lado, H Lázare-Iglesias… - Biomedicines, 2020 - mdpi.com
The aim of this study was to fabricate novel self-supporting tacrolimus suppositories using
semisolid extrusion 3-dimensional printing (3DP) and to investigate their efficacy in an …

[HTML][HTML] Prediction of Alzheimer's disease dementia with MRI beyond the short-term: Implications for the design of predictive models

A Moscoso, J Silva-Rodríguez, JM Aldrey, J Cortés… - NeuroImage: Clinical, 2019 - Elsevier
Magnetic resonance imaging (MRI) volumetric measures have become a standard tool for
the detection of incipient Alzheimer's Disease (AD) dementia in mild cognitive impairment …

[HTML][HTML] Effects of Loigolactobacillus coryniformis K8 CECT 5711 on the Immune Response of Elderly Subjects to COVID-19 Vaccination: A Randomized Controlled …

A Fernández-Ferreiro, FJ Formigo-Couceiro… - Nutrients, 2022 - mdpi.com
Elderly people are particularly vulnerable to COVID-19, with a high risk of developing severe
disease and a reduced immune response to the COVID-19 vaccine. A randomized, placebo …

Texture analysis of high-resolution dedicated breast 18 F-FDG PET images correlates with immunohistochemical factors and subtype of breast cancer

A Moscoso, A Ruibal, I Dominguez-Prado… - European journal of …, 2018 - Springer
Purpose This study aims to determine whether PET textural features measured with a new
dedicated breast PET scanner reflect biological characteristics of breast tumors. Methods …