[HTML][HTML] -Omic Approaches and Treatment Response in Rheumatoid Arthritis

A Madrid-Paredes, J Martín, A Márquez - Pharmaceutics, 2022 - mdpi.com
Rheumatoid arthritis (RA) is an inflammatory disorder characterized by an aberrant
activation of innate and adaptive immune cells. There are different drugs used for the …

Non-HER2 signaling pathways activated in resistance to anti-HER2 therapy in breast cancer

A Madrid-Paredes, M Canadas-Garre… - Breast cancer research …, 2015 - Springer
HER2 receptor is overexpressed approximately in 20% of human breast cancer (BC) and is
a poor prognostic factor. Although therapies targeting this receptor have improved the …

Association of ABCB1 and VEGFA gene polymorphisms with breast cancer susceptibility and prognosis

A Madrid-Paredes, MÁ Casado-Combreras… - … -Research and Practice, 2020 - Elsevier
Breast cancer (BC) is the most common cause of cancer-related death in women worldwide.
Several ABCB1 and VEGFA gene polymorphisms, such as ABCB1-G1199 T/A (rs2229109) …

ABCB1 gene polymorphisms and response to chemotherapy in breast cancer patients: A meta-analysis

A Madrid-Paredes, M Cañadas-Garre… - Surgical Oncology, 2017 - Elsevier
The ABCB1 gene encodes the P-glycoprotein, an efflux pump for some antineoplastic
agents which acts as a resistance mechanism to chemotherapy. Three SNPs (C3435T …

[HTML][HTML] Impact of nutritional and educational support on home enteral nutrition

A Madrid-Paredes, S Leyva-Martínez… - Journal of Health …, 2023 - Springer
Abstract Background Home Enteral Nutrition (HEN) is used to prevent or correct malnutrition
in outpatients. Due to the complexity of this process, the indication, follow-up, and results of …

De novo resistance biomarkers to anti-HER2 therapies in HER2-positive breast cancer

A Madrid-Paredes, M Cañadas-Garre… - …, 2015 - Future Medicine
Therapies targeting HER2 receptor, overexpressed in 20% breast cancer (BC), improved
prognosis, however ̃62% patients experiment progression during the first year. Molecular …

ABCB1 C3435T gene polymorphism as a potential biomarker of clinical outcomes in HER2-positive breast cancer patients

A Madrid-Paredes, M Cañadas-Garre… - Pharmacological …, 2016 - Elsevier
HER2-positive breast cancer patients treated with trastuzumab schemes have good initial
clinical outcomes. Despite this beneficial effect, many patients experiment resistance to …

OP0102 IDENTIFICATION OF NEW RISK LOCI AND PATHWAYS INVOLVED IN GCA PATHOGENESIS BY A GENOME-WIDE STUDY

…, L Ortiz-Fernández, M Kerick, A Madrid-Paredes… - 2023 - ard.bmj.com
Background Giant cell arteritis (GCA) is a chronic large-vessel vasculitis that affects mainly
the aorta and its primary branches, and in Western countries is the most common form of …

Home Enteral Nutrition in Adults: Effectiveness of Nutritional Therapy and Educational Programme

A Madrid-Paredes, S Leyva-Martínez, V Ávila-Rubio… - 2021 - researchsquare.com
Purpose Home Enteral Nutrition (HEN) is used to prevent or correct malnutrition in
outpatients. Due to the complexity of this process, the indication, follow-up, and results of an …

CP-039 Prescription profile and impact after the pegylated liposomal doxorubicin shortage alert

AM Paredes, I Vallejo, M Carrasco, C Valencia… - 2015 - ejhp.bmj.com
Background The normal supply of Caelyx was interrupted worldwide in December 2011.
Because of the limited number of vials available, medicines agencies established a plan to …