Managing incidental findings in human subjects research: analysis and recommendations
Researchers, institutional review boards (IRBs), participants in human subjects research,
and their families face an important but largely neglected problem—how should incidental …
and their families face an important but largely neglected problem—how should incidental …
Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis
Background Structural retinal imaging biomarkers are important for early recognition and
monitoring of inflammation and neurodegeneration in multiple sclerosis. With the …
monitoring of inflammation and neurodegeneration in multiple sclerosis. With the …
[HTML][HTML] The Kepler characterization of the variability among A-and F-type stars-I. General overview
…, P Bradley, V Antoci, M Roth, B Leroy… - Astronomy & …, 2011 - aanda.org
Context. The Kepler spacecraft is providing time series of photometric data with
micromagnitude precision for hundreds of AF type stars. Aims. We present a first general …
micromagnitude precision for hundreds of AF type stars. Aims. We present a first general …
Massive Dirac fermions and Hofstadter butterfly in a van der Waals heterostructure
van der Waals heterostructures constitute a new class of artificial materials formed by
stacking atomically thin planar crystals. We demonstrated band structure engineering in a …
stacking atomically thin planar crystals. We demonstrated band structure engineering in a …
Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label …
S Russell, J Bennett, JA Wellman, DC Chung, ZF Yu… - The Lancet, 2017 - thelancet.com
Background Phase 1 studies have shown potential benefit of gene replacement in RPE65-
mediated inherited retinal dystrophy. This phase 3 study assessed the efficacy and safety of …
mediated inherited retinal dystrophy. This phase 3 study assessed the efficacy and safety of …
Scanning tunnelling microscopy and spectroscopy of ultra-flat graphene on hexagonal boron nitride
Graphene has demonstrated great promise for future electronics technology as well as
fundamental physics applications because of its linear energy–momentum dispersion …
fundamental physics applications because of its linear energy–momentum dispersion …
High and rising economic costs of biological invasions worldwide
Biological invasions are responsible for substantial biodiversity declines as well as high
economic losses to society and monetary expenditures associated with the management of …
economic losses to society and monetary expenditures associated with the management of …
[HTML][HTML] Emergence of superlattice Dirac points in graphene on hexagonal boron nitride
M Yankowitz, J Xue, D Cormode… - Nature physics, 2012 - nature.com
The Schrödinger equation dictates that the propagation of nearly free electrons through a
weak periodic potential results in the opening of bandgaps near points of the reciprocal …
weak periodic potential results in the opening of bandgaps near points of the reciprocal …
Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial
AM Maguire, KA High, A Auricchio, JF Wright… - The Lancet, 2009 - thelancet.com
Background Gene therapy has the potential to reverse disease or prevent further
deterioration of vision in patients with incurable inherited retinal degeneration. We therefore …
deterioration of vision in patients with incurable inherited retinal degeneration. We therefore …
[HTML][HTML] Managing incidental findings and research results in genomic research involving biobanks and archived data sets
…, BM Knoppers, BA Koenig, IS Kohane, B LeRoy… - Genetics in …, 2012 - nature.com
Biobanks and archived data sets collecting samples and data have become crucial engines
of genetic and genomic research. Unresolved, however, is what responsibilities biobanks …
of genetic and genomic research. Unresolved, however, is what responsibilities biobanks …