Clinical applications of laser speckle contrast imaging: a review
W Heeman, W Steenbergen… - … of biomedical optics, 2019 - spiedigitallibrary.org
When a biological tissue is illuminated with coherent light, an interference pattern will be
formed at the detector, the so-called speckle pattern. Laser speckle contrast imaging (LSCI) …
formed at the detector, the so-called speckle pattern. Laser speckle contrast imaging (LSCI) …
[HTML][HTML] The role of vasoactive agents in the resuscitation of microvascular perfusion and tissue oxygenation in critically ill patients
EC Boerma, C Ince - Intensive care medicine, 2010 - Springer
Purpose The clinical use of vasoactive drugs is not only intended to improve systemic
hemodynamic variables, but ultimately to attenuate derangements in organ perfusion and …
hemodynamic variables, but ultimately to attenuate derangements in organ perfusion and …
[HTML][HTML] Quantifying bedside-derived imaging of microcirculatory abnormalities in septic patients: a prospective validation study
EC Boerma, KR Mathura, PHJ van der Voort… - Critical care, 2005 - Springer
Introduction The introduction of orthogonal polarization spectral (OPS) imaging in clinical
research has elucidated new perspectives on the role of microcirculatory flow abnormalities …
research has elucidated new perspectives on the role of microcirculatory flow abnormalities …
Second consensus on the assessment of sublingual microcirculation in critically ill patients: results from a task force of the European Society of Intensive Care …
C Ince, EC Boerma, M Cecconi, D De Backer… - Intensive care …, 2018 - Springer
Purpose Hand-held vital microscopes (HVMs) were introduced to observe sublingual
microcirculatory alterations at the bedside in different shock states in critically ill patients …
microcirculatory alterations at the bedside in different shock states in critically ill patients …
Relationship between sublingual and intestinal microcirculatory perfusion in patients with abdominal sepsis
EC Boerma, PHJ van der Voort, PE Spronk… - Critical care …, 2007 - journals.lww.com
Objective: To evaluate the relation between sublingual and intestinal microcirculatory
alterations in patients with abdominal sepsis. Design: Prospective observational study …
alterations in patients with abdominal sepsis. Design: Prospective observational study …
Effects of nitroglycerin on sublingual microcirculatory blood flow in patients with severe sepsis/septic shock after a strict resuscitation protocol: a double-blind …
EC Boerma, M Koopmans, A Konijn… - Critical care …, 2010 - journals.lww.com
Objectives: Microcirculatory alterations have been associated with morbidity and mortality in
human sepsis. Such alterations occur despite pressure-guided resuscitation. Earlier data …
human sepsis. Such alterations occur despite pressure-guided resuscitation. Earlier data …
[HTML][HTML] Microcirculatory blood flow as a tool to select ICU patients eligible for fluid therapy
A Pranskunas, M Koopmans, PM Koetsier… - Intensive care …, 2013 - Springer
Purpose The aim of this study is to assess the incidence of sublingual microcirculatory flow
alterations, according to a predefined arbitrary cutoff value, in patients with “clinical signs of …
alterations, according to a predefined arbitrary cutoff value, in patients with “clinical signs of …
Central venous-arterial pCO2 difference as a tool in resuscitation of septic patients
PA van Beest, MC Lont, ND Holman, B Loef… - Intensive care …, 2013 - Springer
Purpose To investigate the interchangeability of mixed and central venous-arterial carbon
dioxide differences and the relation between the central difference (p CO 2 gap) and cardiac …
dioxide differences and the relation between the central difference (p CO 2 gap) and cardiac …
[HTML][HTML] Current use of vasopressors in septic shock
Background Vasopressors are commonly applied to restore and maintain blood pressure in
patients with sepsis. We aimed to evaluate the current practice and therapeutic goals …
patients with sepsis. We aimed to evaluate the current practice and therapeutic goals …
International study on microcirculatory shock occurrence in acutely ill patients
NAR Vellinga, EC Boerma, M Koopmans… - Critical care …, 2015 - journals.lww.com
Objectives: Microcirculatory alterations are associated with adverse outcome in subsets of
critically ill patients. The prevalence and significance of microcirculatory alterations in the …
critically ill patients. The prevalence and significance of microcirculatory alterations in the …