Lactoferrin (LF) is a first-line defense protein with a pleiotropic functional pattern that
includes anti-inflammatory, immunomodulatory, antiviral, antibacterial, and antitumoral …

Gellan gum, kappa-carrageenan and alginates are natural polysaccharides able to interact
with different cations that can be used to elaborate ion-activated in situ gelling systems for …

Although intravitreal administration of anti-infectives represents the standard treatment for
infectious endophthalmitis, the knowledge about their pharmacokinetics is still limited. In this …

Nanostructured lipid carriers (NLC) are novel lipidic nanosystems that provide significant
improvements in terms of high drug loading capacity and controlled drug release. The …

This paper proposes an approach to improve drug loading capacity and release properties
of poly (2-hydroxyethyl methacrylate)(p (HEMA)) soft contact lenses based on the …

This research study describes the design, optimization, and characterization of two different
types of chitosan-based nanoparticles as novel drug delivery systems of a protein drug …

Drug nanosuspensions (NSs) show a significant potential to improve loading and release
properties of the poorly water soluble drug triamcinolone acetonide (TA) from poly …

Biodegradable poly (lactic-co-glycolic acid) microspheres (PLGA MSs) are attractive delivery
systems for site-specific maintained release of therapeutic active substances into the …

Background: the present work describes the preparation, characterization and optimization
of eight types of PLGA-based nanosystems (nanospheres and nanocapsules) as innovative …

Cystinosis is a rare autosomal recessive disorder in which cystine crystals accumulate within
the lysosomes of various organs, including the cornea. Ocular treatment is based on the …