The increasing complexity of real-world optimization problems raises new challenges to
evolutionary computation. Responding to these challenges, distributed evolutionary …

As a chronic inflammatory disease of the liver, the pa-thogenic mechanisms of autoimmune
hepatitis (AIH) have not yet been elucidated, with prognosis and diagnosis remaining …

As a conserved protein interaction module that recognizes and binds to acetylated lysine,
bromodomain (BRD) contains a deep, largely hydrophobic acetyl lysine binding site …

Background In clinical practice, there is considerable variation in the timing of the initiation of
maintenance dialysis for patients with stage V chronic kidney disease, with a worldwide …

Social learning in particle swarm optimization (PSO) helps collective efficiency, whereas
individual reproduction in genetic algorithm (GA) facilitates global effectiveness. This …

Context National public insurance for drugs is often based on evidence of comparative
effectiveness and cost-effectiveness. This study describes how that evidence has been used …

Persistent inflammatory responses participate in the pathogenesis of adverse ventricular
remodeling after myocardial infarction (MI). We hypothesized that regulatory T (Treg) cells …

Purely organic room-temperature phosphorescence has attracted attention for bioimaging
but can be quenched in aqueous systems. Here we report a water-soluble ultralong organic …

The aim of this study was to investigate the correlations between serum calcium and clinical
outcomes in patients with coronavirus disease 2019 (COVID-19). In this retrospective study …

Objective. To analyze the relative influence of factors in decisions for public insurance
coverage of new drugs in Australia. Data Sources. Evidence presented at meetings of the …