Discoveries over the past decade portend a paradigm shift in molecular biology. Evidence
suggests that RNA is not only functional as a messenger between DNA and protein but also …

Background Recent advances in genomewide studies have revealed the abundance of long
non-coding RNAs (lncRNAs) in mammalian transcriptomes. The ENCODE Consortium has …

Processing-induced transformations (PITs) during pharmaceutical manufacturing are well
known but difficult to predict and often difficult to control. This review of the concepts of …

This study describes comprehensive polling of transcription start and termination sites and
analysis of previously unidentified full-length complementary DNAs derived from the mouse …

Oncogene-induced senescence (OIS) is crucial for tumour suppression. Senescent cells
implement a complex pro-inflammatory response termed the senescence-associated …

Deterioration of the hippocampus occurs in elderly individuals with and without dementia,
yet individual variation exists in the degree and rate of hippocampal decay. Determining the …

Studied the relation among need for cognition (NFC), message processing, and persuasion.
57 pairs of undergraduates holding approximately the same attitude toward instituting senior …

Small interfering RNA (siRNA) and microRNA silence genes at the transcriptional,
posttranscriptional, and/or translational level. Using human tissue culture cells, we show that …

Purpose Circulating tumor cells (CTCs) may have utility as surrogate biomarkers and
“virtual” biopsies. We report the clinical significance and molecular characteristics of CTCs …

A “fast-drying” method to accelerate the fluid bed drying process is presented. It relies on
concepts of heat and mass transfer with real-time near-infrared (NIR) monitoring of moisture …