The transforming growth factor-beta (TGFβ) superfamily encompasses widespread and
evolutionarily conserved polypeptide growth factors that regulate and orchestrate growth …

Objective Gut microbiota metabolises bile acids (BA). As dysbiosis has been reported in
inflammatory bowel diseases (IBD), we aim to investigate the impact of IBD-associated …

We report on the creation of ultracold heteronuclear molecules assembled from fermionic K
40 and bosonic Rb 87 atoms in a 3D optical lattice. Molecules are produced at a …

Background Patients with primary biliary cholangitis who have an inadequate response to
therapy with ursodeoxycholic acid are at high risk for disease progression. Fibrates, which …

The medical image analysis field has traditionally been focused on the development of
organ-, and disease-specific methods. Recently, the interest in the development of more …

Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is an
autosomal recessive disease caused by mutations in the autoimmune regulator (AIRE) …

Reconstruction methods from biplanar X-rays provide 3D analysis of spinal deformities for
patients in standing position with a low radiation dose. However, such methods require an …

Background Irritable bowel syndrome (IBS) is a multifactorial disease for which a dysbiosis
of the gut microbiota has been described. Bile acids (BA) could play a role as they are …

Background & Aims Alcoholic liver disease (ALD) is a leading cause of liver failure and
mortality. In humans, severe alcoholic hepatitis is associated with key changes to intestinal …

Combined archaeological and ecological investigations in a large ancient oak forest in
Central France have revealed a dense network of ancient human settlements dating from …