We describe the case of a young child with multidrug-resistant tuberculosis, treated with
linezolid. The child developed severe neutropenia after 5 months of treatment. Filgrastim …

Background Boceprevir and telaprevir are two new drugs approved by the European
Medicines Agency for the treatment of hepatitis C genotype 1. They are used in combination …

Background In humans, lactase activity continues after weaning and in adulthood in about
30% of the population (lactase persistence), but in the others the lactase enzyme is absent …

Background Institutions related to healthcare quality, such as the Joint Commission,
recognise that reconciliation errors (REs) compromise the safe use of medicines. Purpose …

Background In our hospital there is a protocol for preoperative Hb optimization with the aim
of reducing blood transfusions in patients with anaemia and upcoming surgery. Purpose To …

Background Daptomycin's licensed indications are complicated skin and soft tissue
infections (cSSTI), right-sided endocarditis due to Staphylococcus aureus (SA) and …

Background Abiraterone was established in a randomised placebo-controlled multicentre
phase 3 clinical study for patients who had received prior docetaxel (n= 1195). The median …

Background The administration of glutamine (GLU) intravenously as part of protein intake in
patients who are given parenteral nutrition (PN) is associated with fewer infectious …

Background Determination of thymidylate synthase (TS) levels in tumour tissue versus
control tissue is useful in our hospital when selecting patients who can benefit from …

Background Biosimilar medicines are developed independently after the patent protecting
the original product has expired. The original products are followed by versions of original …