Abstract Introduction Dravet Syndrome (DS) is a severe, developmental epileptic
encephalopathy (DEE) that begins in infancy and is characterized by pharmaco-resistant …

Backgroud Neoadjuvant treatment based on the combination of trastuzumab plus
chemotherapy is the standard of care in patients with HER2-positive early or locally …

Background Subcutaneous (SC) versus intravenous (IV) administration is advantageous in
terms of patient convenience and hospital efficiency. This study aimed to compare the effect …

Background HIV–HCV coinfection produces high morbi-mortality. Direct-acting antivirals
(DAAs) have shown high efficacy, although special attention should be paid to the risk of …

Objective: The purpose of this study was to analyse the effectiveness and safety of first-line
treatment of metastatic colorectal cancer (CRCm) in older patients treated in a tertiary …

Background and Importance The appropriate use of antibiotics and their clinical impact is a
necessary field of study to address the high incidence of resistance. Aim and Objectives To …

Objetivo: evaluar la contribución del farmacéutico mediante el análisis de la prescripción
potencialmente inapropiada y la conciliación del tratamiento domiciliario en la unidad de …

Background Renal cell carcinoma (RCC) represents only 2-3% of all cancers. Sunitinib is a
standard initial therapy in advanced and metastatic renal cell carcinoma. Purpose A …

Results There were 28 patients studied, with an average of 10 treatment regimens prior to
starting salvage therapy (SD= 3.5; 95% CI, 8.9-11.1). A total of 85.7% patients had treatment …

Background and importance The increase in life expectancy, the higher incidence of cancer
in elderly patients and the lack of clinical trials in these patients makes it necessary to carry …