Background and Importance Lebrikizumab, tralokinumab and dupilumab are anti-interleukin-
13 monoclonal antibody used as therapy in patients with moderate to severe atopic …

Background and Importance Patients with non-small-cell lung cancer (NSCLC) and
epidermal growth factor receptor (EGFR) exon 20 insertion mutations have poor prognosis …

Background and Importance Galcanezumab is a drug indicated for migraine prophylaxis.
People with migraine experience significant functional and quality of life (QoL) impairment …

Background Antiretroviral treatment with a three drug-regimen is the initial treatment
recommended for chronic HIV infection. For various reasons, the combination of three drugs …

Background and Importance Appropriate optimisation of biologic agents in immune-
mediated inflammatory diseases can improve treatment efficiency by decreasing number of …

Background and Importance Pharmaceutical proposals (PPs) in a multidisciplinary
programme (MP) for immune-mediated inflammatory diseases could improve drug …

Background A safety alert about the possibility of a potentially fatal interaction in patients,
especially neonates, has been issued by the FDA. Patients treated with ceftriaxone and …

Background The pomalidomide pivotal clinical trial was recently published in Lancet
Oncology (PubMed PMID: 24007748). Pomalidomide shows a significant benefit on overall …

Background Delayed chemotherapy-induced nausea and vomiting (dCINV) are common
adverse events and appear within 24 h of receiving highly emetogenic drugs: cisplatin …

Background Intravenous immunoglobulins (IgIV) represent a therapeutic option with high
cost and limited availability. As a consequence it is necessary to evaluate their use basing it …