User profiles for "author:Mathew Suji Eapen"

Dr Mathew Suji Eapen

Mucpharm Pty Ltd, University of New South Wales
Verified email at unsw.edu.au
Cited by 3031

Epithelial–mesenchymal transition, a spectrum of states: Role in lung development, homeostasis, and disease

MK Jolly, C Ward, MS Eapen, S Myers… - Developmental …, 2018 - Wiley Online Library
Epithelial–mesenchymal transition (EMT) plays key roles during lung development and
many lung diseases such as chronic obstructive pulmonary disease (COPD), lung cancer …

Airway inflammation in chronic obstructive pulmonary disease (COPD): a true paradox

MS Eapen, S Myers, EH Walters… - Expert review of …, 2017 - Taylor & Francis
Introduction: Chronic obstructive pulmonary disease (COPD) is primarily an airway
condition, which mainly affects cigarette smokers and presents with shortness of breath that …

The rise of electronic nicotine delivery systems and the emergence of electronic-cigarette-driven disease

KD McAlinden, MS Eapen, W Lu… - American Journal of …, 2020 - journals.physiology.org
Abstract In 2019, the United States experienced the emergence of the vaping-associated
lung injury (VALI) epidemic. Vaping is now known to result in the development and …

[HTML][HTML] Smoking upregulates angiotensin-converting enzyme-2 receptor: a potential adhesion site for novel coronavirus SARS-CoV-2 (Covid-19)

SJ Brake, K Barnsley, W Lu, KD McAlinden… - Journal of clinical …, 2020 - mdpi.com
The epicenter of the original outbreak in China has high male smoking rates of around 50%,
and early reported death rates have an emphasis on older males, therefore the likelihood of …

[HTML][HTML] Implications of the second wave of COVID-19 in India

P Asrani, MS Eapen, MI Hassan… - The Lancet Respiratory …, 2021 - thelancet.com
The second wave of COVID-19 in India has had severe consequences in the form of
spiralling cases, reduced supplies of essential treatments, and increased deaths particularly …

[HTML][HTML] Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD)

MS Eapen, PM Hansbro, K McAlinden, RY Kim… - Scientific reports, 2017 - nature.com
We explore potential dysregulation of macrophage phenotypes in COPD pathogenesis
through integrated study of human small airway tissue, bronchoalveolar lavage (BAL) and …

[HTML][HTML] IQOS exposure impairs human airway cell homeostasis: direct comparison with traditional cigarette and e-cigarette

SS Sohal, MS Eapen, VGM Naidu… - ERJ open research, 2019 - Eur Respiratory Soc
Heat-not-burn (HNB) devices can alter vital physiological functions in the lung. HNB devices
may not be a safer option than cigarette smoking or eCig vaping; this does not support the …

[HTML][HTML] Anti-inflammatory activity of fucoidan extracts in vitro

T Ahmad, MS Eapen, M Ishaq, AY Park, SS Karpiniec… - Marine drugs, 2021 - mdpi.com
Fucoidans are sulfated, complex, fucose-rich polymers found in brown seaweeds.
Fucoidans have been shown to have multiple bioactivities, including anti-inflammatory …

[HTML][HTML] Endothelial to mesenchymal transition: a precursor to post-COVID-19 interstitial pulmonary fibrosis and vascular obliteration?

MS Eapen, W Lu, AV Gaikwad… - European …, 2020 - Eur Respiratory Soc
Endothelial to mesenchymal transition: a precursor to post-COVID-19 interstitial pulmonary
fibrosis and vascular obliteration? | European Respiratory Society Skip to main content Main …

COVID-19 and vaping: risk for increased susceptibility to SARS-CoV-2 infection?

KD McAlinden, MS Eapen, W Lu, C Chia… - European …, 2020 - Eur Respiratory Soc
With great interest we read and commend the study done by Russo et al.[1], highlighting
their findings that nicotine induces an increase in angiotensin-converting enzyme 2 (ACE-2) …