Background The first publication of this review in Issue 3, 2005 included studies up to
November 2003. This update adds studies to December 2006 and focuses on application of …

Background This is an updated version of the original Cochrane review published in Issue 3,
2005 of The Cochrane Library. For many years antidepressant drugs have been used to …

Long‐term opioid management for chronic noncancer pain - Noble, M - 2010 | Cochrane
Library Skip to Content Cookies Our site uses cookies to improve your experience. You can …

Background Duloxetine is a balanced serotonin and noradrenaline reuptake inhibitor
licensed for the treatment of major depressive disorders, urinary stress incontinence and the …

Background Antiepileptic drugs have been used in pain management since the 1960s.
Pregabalin is a recently developed antiepileptic drug also used in management of chronic …

Background This review is an update of a review published in 2011, itself a major update of
previous reviews published in 2005 and 2000, investigating the effects of gabapentin in …

Background Anticonvulsant drugs have been used in the management of pain since the
1960s. The clinical impression is that they are useful for chronic neuropathic pain, especially …

Objective: To determine effectiveness and adverse effects of anticonvulsant drugs in
management of pain. Design: Systematic review of randomised controlled trials of …

Background Amitriptyline is a tricyclic antidepressant that is widely used to treat chronic
neuropathic pain (pain due to nerve damage) and fibromyalgia, and is recommended in …

Objective: To review the effectiveness and safety of topical non-steroidal anti-inflammatory
drugs in acute and chronic pain conditions. Design: Quantitive systematic review of …