User profiles for "author:Richard Franklin"
Richard C FranklinProfessor, Public Health - Injury Prevention and Safety Promotion, James Cook University Verified email at jcu.edu.au Cited by 111870 |
[HTML][HTML] Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
JA McCubrey, LS Steelman, WH Chappell… - … et Biophysica Acta (BBA …, 2007 - Elsevier
Growth factors and mitogens use the Ras/Raf/MEK/ERK signaling cascade to transmit
signals from their receptors to regulate gene expression and prevent apoptosis. Some …
signals from their receptors to regulate gene expression and prevent apoptosis. Some …
Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.
F Chang, LS Steelman, JT Lee… - Leukemia …, 2003 - search.ebscohost.com
Abstract The Ras/Raf/Mitogen-activated protein kinase/ERK kinase (MEK)/extracellular-
signal-regulated kinase (ERK) cascade couples signals from cell surface receptors to …
signal-regulated kinase (ERK) cascade couples signals from cell surface receptors to …
Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance
JA McCubrey, LS Steelman, SL Abrams, JT Lee… - Advances in enzyme …, 2006 - Elsevier
The Ras/Raf/MEK/ERK and PI3K/PTEN/AKT signaling cascades play critical roles in the
transmission of signals from growth factor receptors to regulate gene expression and …
transmission of signals from growth factor receptors to regulate gene expression and …
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
Background Reliable and timely information on the leading causes of death in populations,
and how these are changing, is a crucial input into health policy debates. In the Global …
and how these are changing, is a crucial input into health policy debates. In the Global …
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
Background Non-fatal health outcomes from diseases and injuries are a crucial
consideration in the promotion and monitoring of individual and population health. The …
consideration in the promotion and monitoring of individual and population health. The …
The global burden of cancer 2013
C Fitzmaurice, D Dicker, A Pain, H Hamavid… - JAMA …, 2015 - jamanetwork.com
Importance Cancer is among the leading causes of death worldwide. Current estimates of
cancer burden in individual countries and regions are necessary to inform local cancer …
cancer burden in individual countries and regions are necessary to inform local cancer …
The global burden of injury: incidence, mortality, disability-adjusted life years and time trends from the Global Burden of Disease study 2013
Background The Global Burden of Diseases (GBD), Injuries, and Risk Factors study used
the disability-adjusted life year (DALY) to quantify the burden of diseases, injuries, and risk …
the disability-adjusted life year (DALY) to quantify the burden of diseases, injuries, and risk …
Case study research: Foundations and methodological orientations
H Harrison, M Birks, R Franklin… - Forum qualitative …, 2017 - qualitative-research.net
Over the last forty years, case study research has undergone substantial methodological
development. This evolution has resulted in a pragmatic, flexible research approach …
development. This evolution has resulted in a pragmatic, flexible research approach …
[HTML][HTML] Hearing loss prevalence and years lived with disability, 1990–2019: findings from the Global Burden of Disease Study 2019
Background Hearing loss affects access to spoken language, which can affect cognition and
development, and can negatively affect social wellbeing. We present updated estimates …
development, and can negatively affect social wellbeing. We present updated estimates …
Reactive oxygen species-induced activation of the MAP kinase signaling pathways
JA McCubrey, MM LaHair… - Antioxidants & redox …, 2006 - liebertpub.com
An abundance of scientific literature exists demonstrating that oxidative stress influences the
MAPK signaling pathways. This review summarizes these findings for the ERK, JNK, p38 …
MAPK signaling pathways. This review summarizes these findings for the ERK, JNK, p38 …