Clinical outcomes after combination treatment with ceftazidime/avibactam and aztreonam for NDM-1/OXA-48/CTX-M-15-producing Klebsiella pneumoniae infection

E Shaw, A Rombauts, F Tubau… - Journal of …, 2018 - academic.oup.com
Sir, The growing spread of bacteria producing carbapenemases, such as the New Delhi
MBL (NDM), 1 has created an urgent need to identify effective therapeutic options that can …

Development and validation of a measurement procedure based on ultra-high performance liquid chromatography-tandem mass spectrometry for simultaneous …

R Rigo-Bonnin, A Ribera, A Arbiol-Roca… - Clinica chimica acta, 2017 - Elsevier
Background The administration of β-lactam antibiotics in continuous infusion could let
optimize the pharmacokinetic/pharmacodynamic parameters, especially in the treatment of …

[HTML][HTML] Utilización de Subjective Global Assessment, patient-generated subjective global assessment y nutritional risk screening 2002 para evaluar el estado …

MB Badia-Tahull, S Cobo-Sacristán… - Nutricion …, 2014 - SciELO Espana
Objective: To evaluate the nutritional status of non-critically ill digestive surgery patients at
the moment of parenteral nutrition initiation using three different nutritional test tools and to …

Management of tizanidine withdrawal syndrome: a case report

A Suárez-Lledó, A Padullés, T Lozano… - Clinical Medicine …, 2018 - journals.sagepub.com
Most drugs that act on the central nervous system (CNS) require dose titration to avoid
withdrawal syndrome. Tizanidine withdrawal syndrome is caused by adrenergic discharge …

Continuous infusion of piperacillin/tazobactam and meropenem in ICU patients without renal dysfunction: are patients at risk of underexposure?

E Esteve-Pitarch, VD Gumucio-Sanguino… - European Journal of …, 2021 - Springer
Abstract Background and Objectives Morbidity and mortality from serious infections are
common in intensive care units (ICUs). The appropriateness of the antibiotic treatment is …

[HTML][HTML] Long-Term Effects of a Stepwise, Multimodal, Non-Restrictive Antimicrobial Stewardship Programme for Reducing Broad-Spectrum Antibiotic Use in the ICU

M Ronda, VD Gumucio-Sanguino, E Shaw, R Granada… - Antibiotics, 2024 - mdpi.com
Information on the long-term effects of non-restrictive antimicrobial stewardship (AMS)
strategies is scarce. We assessed the effect of a stepwise, multimodal, non-restrictive AMS …

Measurement of ceftazidime concentration in human plasma by ultra‐performance liquid chromatography–tandem mass spectrometry. Application to critically ill …

R Rigo‐Bonnin, S Cobo‐Sacristán… - Biomedical …, 2016 - Wiley Online Library
Ceftazidime is an antibiotic belonging to the third generation of the cephalosporin family. It is
indicated in the treatment of serious, simple or mixed bacterial infections, and its …

[HTML][HTML] Predictive Factors of Piperacillin Exposure and the Impact on Target Attainment after Continuous Infusion Administration to Critically Ill Patients

J Martínez-Casanova, E Esteve-Pitarch… - Antibiotics, 2023 - mdpi.com
Critically ill patients undergo significant pathophysiological changes that affect antibiotic
pharmacokinetics. Piperacillin/tazobactam administered by continuous infusion (CI) …

Measurement of total and free docetaxel concentration in human plasma by ultra-performance liquid chromatography–tandem mass spectrometry

R Rigo-Bonnin, S Cobo-Sacristán… - … of Pharmaceutical and …, 2016 - Elsevier
Docetaxel is a semi-synthetic taxane with cytotoxic anti-neoplastic activity and, currently
used as anticancer agent in several types of cancer. Docetaxel is highly bound to plasma …

[HTML][HTML] OTAC: Optimization of Antibiotic Therapy in Critically ill patients. Using beta-lactam antibiotics by continuous infusion

E Esteve-Pitarch, A Padullés-Zamora… - Farmacia …, 2019 - Elsevier
Objective To determine the percentage of patients given standard doses of piperacillin/
tazobactam or meropenem by continuous infusion who achieved the target pharmacokinetic …