User profiles for "author:Sandra Appiah"
 | Sandra AppiahAssociate Professor (Reader) of Biochemistry, Middlesex University Verified email at mdx.ac.uk Cited by 127 |
Phytochemical modulation of apoptosis and autophagy: Strategies to overcome chemoresistance in leukemic stem cells in the bone marrow microenvironment
Advances in scientific research and targeted treatment regimes have improved survival rates
for many cancers over the past few decades. However, for some types of leukemia, including …
for many cancers over the past few decades. However, for some types of leukemia, including …
[HTML][HTML] Effects of Immunization With the Soil-Derived Bacterium Mycobacterium vaccae on Stress Coping Behaviors and Cognitive Performance in a “Two Hit” …
Previous studies demonstrate that Mycobacterium vaccae NCTC 11659 (M. vaccae), a soil-
derived bacterium with anti-inflammatory and immunoregulatory properties, is a potentially …
derived bacterium with anti-inflammatory and immunoregulatory properties, is a potentially …
[HTML][HTML] Evaluation of the gut microbiome in association with biological signatures of inflammation in murine polytrauma and shock
SA Appiah, CL Foxx, D Langgartner, A Palmer… - Scientific Reports, 2021 - nature.com
Severe injuries are frequently accompanied by hemorrhagic shock and harbor an increased
risk for complications. Local or systemic inflammation after trauma/hemorrhage may lead to …
risk for complications. Local or systemic inflammation after trauma/hemorrhage may lead to …
Evidence for the outcomes and impact of clinical pharmacy: context of UK hospital pharmacy practice
Objectives The role of clinical pharmacists in hospitals has evolved and continues to
expand. In the UK, outside of a few national policy drivers, there are no agreed priorities …
expand. In the UK, outside of a few national policy drivers, there are no agreed priorities …
[HTML][HTML] Doxorubicin selectively induces apoptosis through the inhibition of a novel isoform of Bcl‑2 in acute myeloid leukaemia MOLM‑13 cells with reduced Beclin 1 …
M Vu, N Kassouf, R Ofili, T Lund… - International …, 2020 - spandidos-publications.com
The overexpression of anti‑apoptotic Bcl‑2 in acute myeloid leukaemia (AML) may contribute
to difficulties in eradicating these cells during chemotherapy. In the present study …
to difficulties in eradicating these cells during chemotherapy. In the present study …
[HTML][HTML] Liposome‑delivered baicalein induction of myeloid leukemia K562 cell death via reactive oxygen species generation
SX Wang, X Wen, C Bell… - Molecular medicine …, 2018 - spandidos-publications.com
Baicalein (BL), a potential cancer chemopreventative flavone, has been reported to inhibit
cancer cell growth by inducing apoptosis and causing cell cycle arrest in various human …
cancer cell growth by inducing apoptosis and causing cell cycle arrest in various human …
Antiinflammatory and hepatoprotective medicinal herbs as potential substitutes for bear bile
Practitioners of traditional Chinese medicine (TCM) commonly prescribe medicinal
formulations relying on the purported synergism of a combination of plant species …
formulations relying on the purported synergism of a combination of plant species …
[HTML][HTML] Betulinic acid–doxorubicin-drug combination induced apoptotic death via ROS stimulation in a relapsed AML MOLM-13 cell model
M Vu, N Kassouf, S Appiah - Antioxidants, 2021 - mdpi.com
In this study, cell death regulation and induction in AML cell line from a relapsed MLL-
rearranged cell model (MOLM-13) was investigated with doxorubin (Dox) and betulinic acid …
rearranged cell model (MOLM-13) was investigated with doxorubin (Dox) and betulinic acid …
[PDF][PDF] Plant substances as alternatives for animal products in traditional medicines
CM Bell, MSJ Simmonds, SS Appiah… - Report submitted to …, 2006 - researchgate.net
The use of traditional medicine (TM) containing ingredients obtained from animals and
plants has maintained its popularity in all regions of the developing world and is gaining in …
plants has maintained its popularity in all regions of the developing world and is gaining in …
Evaluation of the effectiveness of Eladi Keram for the treatment of acne vulgaris: a randomised controlled pilot study
Introduction Acne is a multifactorial and common skin disease which can significantly affect
the quality of life of sufferers. In this study, a topical herbal preparation traditionally used in …
the quality of life of sufferers. In this study, a topical herbal preparation traditionally used in …