Introduction. Novel synthetic 'designer'drugs with stimulant, ecstasy-like (entactogenic)
and/or hallucinogenic properties have become increasingly popular among recreational …

Tricyclic antidepressants remain a common cause of fatal drug poisoning as a result of their
cardiovascular toxicity manifested by ECG abnormalities, arrhythmias and hypotension …

Paracetamol poisoning caused by intentional overdose remains a common cause of
morbidity. In this article the mechanism of toxicity and the clinical effects and treatment of …

Background Paracetamol poisoning is common worldwide. It is treated with intravenous
acetylcysteine, but the standard regimen is complex and associated with frequent adverse …

Objective To describe the patterns and clinical features of toxicity related to recreational use
of mephedrone and other cathinones in the UK using data collected by the National Poisons …

Background: Although intravenous lipid emulsion (ILE) was first used to treat life-threatening
local anesthetic (LA) toxicity, its use has expanded to include both non-local anesthetic (non …

Abstract Context. 4-Iodo-2, 5-dimethoxy-N-(2-methoxybenzyl) phenethylamine (25I-NBOMe)
is a N-methoxybenzyl-substituted phenethylamine with potent serotoninergic effects. We …

Torsades de pointes (TdP) is a characteristic polymorphic ventricular arrhythmia associated
with delayed ventricular repolarization as evidenced on the surface electrocardiogram by QT …

Aims In S eptember 2012 the UK's Commission on Human Medicines (CHM) recommended
changes in the management of paracetamol poisoning: use of a single '100 mg l …

Background Paracetamol overdose is common but patient stratification is suboptimal. We
investigated the usefulness of new biomarkers that have either enhanced liver specificity …