Clinical implications of intravenous drug incompatibilities in critically ill patients

M Benlabed, M Perez, R Gaudy, S Genay… - … Critical Care & Pain …, 2019 - Elsevier
Objective The aim of this review is to analyse the clinical consequences of intravenous drug
incompatibilities in critically ill patients, especially the incidence of organ dysfunctions and …

Strategies to prevent drug incompatibility during simultaneous multi-drug infusion in intensive care units: a literature review

L Négrier, A Martin Mena, G Lebuffe, P Odou… - European Journal of …, 2021 - Springer
Purpose Drug protocols in intensive care units may require the concomitant administration of
many drugs as patients' venous accesses are often limited. A major challenge for clinicians …

Medical devices used in NICU: The main source of plasticisers' exposure of newborns

L Bernard, M Masse, B Boeuf, P Chennell… - Science of The Total …, 2023 - Elsevier
Phthalates and other plasticisers are extensively used in medical devices (MD) from which
they can leach out and lead to potential multiple problems for the patients. This exposure is …

Criteria for choosing an intravenous infusion line intended for multidrug infusion in anaesthesia and intensive care units

A Maiguy-Foinard, S Genay, D Lannoy… - … Critical Care & Pain …, 2017 - Elsevier
Objective The aims are to identify critical parameters influencing the drug mass flow rate of
infusion delivery to patients during multidrug infusion and to discuss their clinical relevance …

Experimental study on infusion devices containing polyvinyl chloride: to what extent are they di (2-ethylhexyl) phthalate-free?

S Genay, C Luciani, B Décaudin, N Kambia… - International journal of …, 2011 - Elsevier
The use of medical devices containing highly criticized phthalates including di (2-ethylhexyl)
phthalate (DEHP) has been challenged by European directive 2007/47/CE, put into effect in …

New SPE-LC-MS/MS method for the simultaneous determination in urine of 22 metabolites of DEHP and alternative plasticizers from PVC medical devices

J Pinguet, N Kerckhove, T Eljezi, C Lambert, E Moreau… - Talanta, 2019 - Elsevier
DiEthylHexylPhthalate (DEHP) can leach out of plasticized PVC medical devices (MD) and
may enter into contact with patients. This phthalate is known for its reprotoxic and endocrine …

Development and validation of an UHPLC-MS/MS method for simultaneous quantification of ibrutinib and its dihydrodiol-metabolite in human cerebrospinal fluid

D Beauvais, JF Goossens, E Boyle, B Allal… - … of Chromatography B, 2018 - Elsevier
Ibrutinib is an orally administered first-in-class irreversible Bruton's tyrosine kinase (BTK)
covalent inhibitor for the treatment of patients with B-cell malignancies. Several isolated …

Quantification of five plasticizers used in PVC tubing through high performance liquid chromatographic-UV detection

T Radaniel, S Genay, N Simon, F Feutry… - … of Chromatography B, 2014 - Elsevier
Searching for alternatives to di-(2-ethylhexyl)-phthalate, a plasticizer that has been widely
used in the manufacturing of PVC medical devices, has become a major challenge since a …

[HTML][HTML] Evaluation of the stability of vancomycin solutions at concentrations used in clinical services

M Masse, S Genay, AM Mena, N Carta… - European Journal of …, 2020 - ejhp.bmj.com
Vancomycin hydrochloride is an antibiotic belonging to the glycopeptide family and acts by
inhibiting the synthesis of the peptidoglycan wall. This antibiotic is active against Gram …

[HTML][HTML] In vitro assessment of the influence of intravenous extension set materials on insulin aspart drug delivery

M Masse, M Maton, S Genay, N Blanchemain… - PLoS …, 2018 - journals.plos.org
Insulin is a frequently prescribed drug in hospitals and is usually administered by syringe
pumps with an extension line which can be made of various materials. Two insulin solutions …